Opportunity Information: Apply for CDC RFA CK24 2401

The Emerging Infections Program (EIP) grant opportunity supports a long-running CDC network created to strengthen the United States' ability to detect, track, and respond to infectious disease threats. The EIP began in 1995 after rising concern about emerging and re-emerging infections, and it grew out of CDC planning that followed the 1992 Institute of Medicine report "Emerging Infections: Microbial Threats to the United States." The central idea is that strong public health surveillance is the backbone of prevention and control, so CDC built a multi-site, population-based network of centers of excellence led through state health departments and closely partnered with academic institutions, local health departments, clinical and public health laboratories, infection control teams, healthcare providers, and CDC. The network is designed to produce timely, high-quality data that can be used directly to shape public health action, clinical guidance, and policy.

At its core, this Notice of Funding Opportunity (NOFO) aims to sustain and enhance the EIP as a multi-site surveillance and applied research platform. The program is built around four major categories of work: (1) active infectious disease surveillance, meaning systematic, proactive case finding rather than relying only on passive reports; (2) applied public health epidemiology and laboratory activities, which can include special studies, advanced testing, and deeper analyses that explain trends and risks; (3) implementation and evaluation of pilot prevention or intervention projects, so promising strategies can be tested in real-world settings and measured for impact; and (4) rapid, flexible response to emergencies and newly emerging infectious disease issues, allowing sites to stand up new surveillance or studies quickly when urgent threats arise. A major theme of the current funding is infrastructure and data modernization, reflecting the need for faster, more standardized, and more interoperable data systems across sites.

The EIP network covers a broad portfolio of infectious disease areas that are especially important for public health decision-making. It conducts active, population-based surveillance and special studies for respiratory viral diseases such as influenza, COVID-19, and RSV; invasive bacterial diseases including antibiotic-resistant infections; foodborne pathogens; and healthcare-associated infections, among other topics. The COVID-19 pandemic is highlighted as a clear example of why a standing, multi-center surveillance platform matters: EIP sites were able to rapidly implement collaborative activities like COVID-NET to track COVID-19 hospitalization rates, describe patient characteristics, and evaluate vaccine effectiveness using consistent methods across multiple locations. The network structure is specifically valued because it enables cross-site comparisons, rapid aggregation of data, and coordinated analyses that are difficult to achieve through isolated efforts.

The NOFO indicates that awardees will be expected to carry out required activities centered on Infrastructure and Data Modernization and on Surveillance and Reporting (referenced as Surveillance and Reporting 1 and 2). Beyond those required elements, the EIP includes multiple established components and topic areas, which may vary by site and public health need. Examples listed include FluSurv-NET for influenza hospitalization surveillance, RSV-NET for RSV, COVID-NET for COVID-19, Active Bacterial Core surveillance (ABCs), FoodNet for foodborne disease surveillance, Healthcare-Associated Infections - Community Interface (HAIC), HPV IMPACT, TickNET for Lyme and other tickborne diseases, and Prion Disease surveillance, along with other infectious disease activities and applicant-specific projects that align with EIP goals. Overall, the expectation is that the network will continue to generate actionable, population-based evidence that supports prevention strategies, informs treatment guidelines, and strengthens readiness for the next infectious disease threat.

Administratively, this is a discretionary cooperative agreement (meaning CDC is expected to have substantial involvement in the work), offered by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), within NCEZID. The funding opportunity number is CDC-RFA-CK24-2401 and the CFDA (Assistance Listing) number is 93.317. The opportunity anticipates about 15 awards. Eligibility is broad and includes state, county, and city or township governments; special districts; tribal governments and tribal organizations; public and private institutions of higher education; nonprofits with or without 501(c)(3) status; and for-profit organizations (including small businesses), with any additional eligibility details subject to the NOFO's specific clarifications. The original application close date listed is June 20, 2023, with electronic submissions due by 11:59 pm ET on the due date. The award ceiling is listed as 0, which typically signals that applicants should refer to the NOFO for detailed budgeting expectations or that ceilings may vary by component, site, or negotiated scope rather than being stated as a single fixed cap in the summary metadata.

  • The Department of Health and Human Services, Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "Emerging Infections Program" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.317.
  • This funding opportunity was created on Apr 21, 2023.
  • Applicants must submit their applications by Jun 20, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 15 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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