Opportunity Information: Apply for RFA OD 19 026
This NIH funding opportunity (RFA-OD-19-026) supports the selection of Clinical Sites for the Environmental Influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (often shortened to the ISPCTN). It uses a UG1 cooperative agreement mechanism, which means awardees are expected to work closely with NIH and the broader network rather than operating as completely independent grantees. The core idea is to strengthen and expand the ability to run pediatric clinical trials in Institutional Development Award (IDeA)-eligible states, with a clear emphasis on reaching children and families in rural and other medically underserved communities.
The role of an awarded Clinical Site is twofold. First, sites are expected to conduct multicenter pediatric clinical trials as part of a coordinated network, helping ensure that children in IDeA states are represented in well-designed studies that may otherwise be concentrated in large, research-intensive urban centers. Second, each site is expected to build lasting pediatric clinical research capacity within its state or region. In practice, that capacity-building focus typically points to improving trial infrastructure and readiness, such as staffing, recruitment and retention systems, regulatory and ethics processes, data collection and quality procedures, and partnerships with community providers so that trials are feasible and sustainable in places that have historically had fewer opportunities to participate.
Eligibility is broad across many U.S.-based organization types, as long as the applicant is based in an IDeA-eligible state and otherwise meets NIH requirements. Eligible applicants include state, county, and local governments; public and private institutions of higher education; independent school districts; special district governments; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The announcement also highlights additional eligible categories such as Historically Black Colleges and Universities, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions, as well as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies.
Foreign participation is explicitly restricted. Non-U.S. (foreign) entities and foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are not eligible. In addition, foreign components, as NIH defines them in its Grants Policy Statement, are not permitted under this opportunity. In other words, the program is designed to build and operate U.S.-based pediatric trial capacity within the targeted IDeA jurisdictions rather than funding international structures.
Administratively, the funding is offered by the National Institutes of Health, Office of the Director, under a discretionary program category, with activity areas spanning education, health, income security, and social services as reflected in the listed CFDA numbers (93.279, 93.310, 93.853, 93.855, 93.859, 93.865). The opportunity originally listed an application due date of December 2, 2019, was created August 30, 2019, and included an award ceiling of $275,000. Overall, the grant is aimed at expanding where and how pediatric clinical trials happen by embedding rigorous, networked research activity in IDeA states and building the on-the-ground capabilities needed to consistently include rural and underserved children in high-quality clinical studies.Apply for RFA OD 19 026
- The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Clinical Sites for the ECHO IDeA States Pediatric Clinical Trials Network - 2 (UG1 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279, 93.310, 93.853, 93.855, 93.859, 93.865.
- This funding opportunity was created on 2019-08-30.
- Applicants must submit their applications by 2019-12-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $275,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
This is an NIH funding opportunity (RFA-OD-19-026) to support the selection of Clinical Sites for the Environmental Influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (ISPCTN).
What does ECHO ISPCTN stand for?
It refers to the Environmental Influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network, often shortened to the ISPCTN.
What is the purpose of this program?
The program is designed to strengthen and expand pediatric clinical trial capacity in Institutional Development Award (IDeA)-eligible states, with a clear emphasis on reaching children and families in rural and other medically underserved communities.
What type of award mechanism is used?
The opportunity uses a UG1 cooperative agreement mechanism.
What does a UG1 cooperative agreement mean for awardees?
A UG1 cooperative agreement indicates that awardees are expected to work closely with NIH and the broader ISPCTN network, rather than operating as completely independent grantees.
What is a Clinical Site expected to do if awarded?
An awarded Clinical Site has two main roles: (1) conduct multicenter pediatric clinical trials as part of a coordinated network, and (2) build lasting pediatric clinical research capacity within its state or region.
What does "conduct multicenter pediatric clinical trials" mean in this context?
It means the Clinical Site participates in clinical trials that involve multiple sites working together, helping ensure children in IDeA states are represented in well-designed studies that might otherwise be concentrated in large, research-intensive urban centers.
What does "capacity building" mean for Clinical Sites?
Capacity building refers to developing durable, local ability to run pediatric clinical trials. The opportunity description points to improvements in trial infrastructure and readiness, such as staffing, recruitment and retention systems, regulatory and ethics processes, data collection and quality procedures, and partnerships with community providers.
Why is there a focus on rural and medically underserved communities?
The program emphasizes expanding access to high-quality pediatric clinical trials in places that have historically had fewer opportunities to participate, including rural and medically underserved communities in IDeA-eligible states.
Who is eligible to apply?
Eligibility is broad across many U.S.-based organization types, as long as the applicant is based in an IDeA-eligible state and meets NIH requirements.
What kinds of U.S. organizations are listed as eligible applicants?
Eligible applicants include state, county, and local governments; public and private institutions of higher education; independent school districts; special district governments; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses.
Are certain institution types specifically highlighted as eligible?
Yes. The announcement highlights additional eligible categories such as Historically Black Colleges and Universities, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly mentioned among the eligible categories.
Are regional organizations eligible?
Yes. Regional organizations are included among the eligible categories mentioned in the opportunity description.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are listed among the additional eligible categories.
Are federal agencies eligible to apply?
The opportunity description notes that eligible federal agencies are included among the eligible categories.
Can foreign (non-U.S.) organizations apply?
No. Non-U.S. (foreign) entities and foreign institutions are explicitly not eligible to apply.
Can a U.S. organization apply if it plans to include a non-domestic component?
No. Non-domestic components of U.S. organizations are not eligible under this opportunity.
Are foreign components allowed under NIH policy for this opportunity?
No. Foreign components, as NIH defines them in its Grants Policy Statement, are not permitted for this opportunity.
Which NIH entity is offering this funding opportunity?
The funding is offered by the National Institutes of Health (NIH), Office of the Director.
Is this a discretionary program?
Yes. The opportunity is identified as being under a discretionary program category.
What activity areas are associated with this opportunity?
The listed activity areas span education, health, income security, and social services, as reflected in the CFDA numbers provided in the opportunity description.
What CFDA numbers are associated with this opportunity?
The opportunity lists CFDA numbers 93.279, 93.310, 93.853, 93.855, 93.859, and 93.865.
What was the application due date listed for this opportunity?
The opportunity originally listed an application due date of December 2, 2019.
When was this opportunity created?
The opportunity was created on August 30, 2019.
What is the award ceiling?
The opportunity included an award ceiling of $275,000.
What is the overall goal of funding these Clinical Sites?
The overall goal is to expand where and how pediatric clinical trials happen by embedding rigorous, networked research activity in IDeA states and building the local capabilities needed to consistently include rural and underserved children in high-quality clinical studies.
Does this opportunity support independent single-site trials?
The description emphasizes multicenter pediatric clinical trials conducted as part of a coordinated network, and a cooperative agreement structure that involves close collaboration with NIH and the broader network.
What kinds of operational improvements are implied by "trial readiness"?
The opportunity description points to areas like staffing, recruitment and retention systems, regulatory and ethics processes, data collection and quality procedures, and partnerships with community providers to make trials feasible and sustainable in historically under-resourced settings.
Why focus on IDeA-eligible states?
Based on the opportunity description, the program targets IDeA-eligible states in order to strengthen and expand pediatric clinical trial capacity in jurisdictions where research infrastructure and trial access have historically been more limited.
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