Clinical Sites for the ECHO IDeA States Pediatric Clinical Trials Network - 2 (UG1 Clinical Trial Required) | RFA OD 19 026

Opportunity Information: Apply for RFA OD 19 026

This NIH funding opportunity (RFA-OD-19-026) supports the selection of Clinical Sites for the Environmental Influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (often shortened to the ISPCTN). It uses a UG1 cooperative agreement mechanism, which means awardees are expected to work closely with NIH and the broader network rather than operating as completely independent grantees. The core idea is to strengthen and expand the ability to run pediatric clinical trials in Institutional Development Award (IDeA)-eligible states, with a clear emphasis on reaching children and families in rural and other medically underserved communities.

The role of an awarded Clinical Site is twofold. First, sites are expected to conduct multicenter pediatric clinical trials as part of a coordinated network, helping ensure that children in IDeA states are represented in well-designed studies that may otherwise be concentrated in large, research-intensive urban centers. Second, each site is expected to build lasting pediatric clinical research capacity within its state or region. In practice, that capacity-building focus typically points to improving trial infrastructure and readiness, such as staffing, recruitment and retention systems, regulatory and ethics processes, data collection and quality procedures, and partnerships with community providers so that trials are feasible and sustainable in places that have historically had fewer opportunities to participate.

Eligibility is broad across many U.S.-based organization types, as long as the applicant is based in an IDeA-eligible state and otherwise meets NIH requirements. Eligible applicants include state, county, and local governments; public and private institutions of higher education; independent school districts; special district governments; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); and small businesses. The announcement also highlights additional eligible categories such as Historically Black Colleges and Universities, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions, as well as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies.

Foreign participation is explicitly restricted. Non-U.S. (foreign) entities and foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are not eligible. In addition, foreign components, as NIH defines them in its Grants Policy Statement, are not permitted under this opportunity. In other words, the program is designed to build and operate U.S.-based pediatric trial capacity within the targeted IDeA jurisdictions rather than funding international structures.

Administratively, the funding is offered by the National Institutes of Health, Office of the Director, under a discretionary program category, with activity areas spanning education, health, income security, and social services as reflected in the listed CFDA numbers (93.279, 93.310, 93.853, 93.855, 93.859, 93.865). The opportunity originally listed an application due date of December 2, 2019, was created August 30, 2019, and included an award ceiling of $275,000. Overall, the grant is aimed at expanding where and how pediatric clinical trials happen by embedding rigorous, networked research activity in IDeA states and building the on-the-ground capabilities needed to consistently include rural and underserved children in high-quality clinical studies.

• The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Clinical Sites for the ECHO IDeA States Pediatric Clinical Trials Network - 2 (UG1 Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279, 93.310, 93.853, 93.855, 93.859, 93.865.
• This funding opportunity was created on 2019-08-30.
• Applicants must submit their applications by 2019-12-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $275,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA OD 19 026

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