Opportunity Information: Apply for CDC RFA PS20 20100101SUPP23
PS20-2010: Integrated HIV Programs for Health Departments to Support Ending the HIV Epidemic in the United States (EHE) Component C mpox Supplement is a CDC supplemental funding opportunity designed to help health departments strengthen and expand existing clinic-based sexual health and HIV prevention services by adding integrated mpox services. In practical terms, the supplement is meant to build on work already happening in STD specialty clinics that participate under PS20-2010, Component C, and to fold mpox vaccination, mpox diagnosis, and mpox treatment services into the routine flow of sexual health care. The overall intent is to make mpox-related prevention and clinical services more accessible and normalized within the same settings where patients already seek HIV prevention and sexual health services, reducing missed opportunities for timely vaccination, testing, and care.
This opportunity is offered by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), specifically under NCHHSTP, and it is structured as a cooperative agreement. That means recipients should expect an active partnership model in which CDC is involved beyond simply issuing funds, often through technical assistance, program expectations, and ongoing collaboration around implementation and performance. The funding falls under the health activity category and is associated with CFDA number 93.270.
Eligibility is limited to governmental entities, including state governments, county governments, and city or township governments. The focus on these applicants aligns with the program goal of supporting public health systems that oversee or directly operate STD specialty clinics and related sexual health infrastructure. The supplement is tied to existing PS20-2010 Component C work, so it is best understood as an expansion of an established program footprint rather than a standalone initiative for new applicants without that baseline clinic participation.
The funding opportunity number is CDC RFA PS20 20100101SUPP23, and it was posted on March 15, 2023, with an original application closing date of April 14, 2023. Applications were required to be submitted electronically by 11:59 pm Eastern Time on the due date. CDC anticipated making 19 awards under this supplement, with an award ceiling of $800,000 per award. The competitive scale suggests CDC intended to resource a defined set of jurisdictions with meaningful support to operationalize integration in real-world clinic settings, potentially covering staffing, service delivery enhancements, workflow updates, and other implementation needs consistent with the supplement purpose.
At its core, the supplement emphasizes integration, meaning mpox services are not treated as an isolated or temporary add-on, but instead incorporated into routine sexual health care and HIV prevention services already being provided at participating STD specialty clinics. This integrated approach typically supports more seamless patient experiences, faster linkage from risk assessment to vaccination or testing, and improved continuity of care, particularly for populations that may be at higher risk for both HIV and mpox or who already rely on STD specialty clinics for stigma-sensitive services. The supplement language points to three main mpox service domains to be incorporated: vaccination (prevention), diagnosis (testing and clinical identification), and treatment (care and management pathways), all positioned within existing sexual health and HIV prevention service delivery models.
Overall, the opportunity reflects a public health strategy of leveraging established HIV and sexual health clinic infrastructure to respond to mpox in a way that is practical, sustainable, and accessible. By funding health departments to embed mpox vaccination, diagnostic capacity, and treatment pathways into routine clinic operations, CDC is aiming to strengthen comprehensive sexual health services while supporting broader efforts aligned with Ending the HIV Epidemic (EHE) priorities through integrated, patient-centered care.Apply for CDC RFA PS20 20100101SUPP23
- The Department of Health and Human Services, Centers for Disease Control - NCHHSTP in the health sector is offering a public funding opportunity titled "PS20-2010: Integrated HIV Programs for Health Departments to Support Ending the HIV Epidemic in the United States (EHE) Component C mpox Supplement" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.270.
- This funding opportunity was created on Mar 15, 2023.
- Applicants must submit their applications by Apr 14, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $800,000.00 in funding.
- The number of recipients for this funding is limited to 19 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments.
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